CD20 on B Cells, Blood, Mayo RefLab
SoftLab Order Code
CD20B
Epic Order Name
CD20 on B Cells, Mayo RefLab
Epic Order ID
LAB3909
Laboratory
Reference Lab
Mayo
Additional Test Information
Useful for:
Evaluation of CD19 deficiency in patients with a suspected CD19 deficiency (humoral immunodeficiency).
Confirming complete absence of B cells in suspected primary humoral immunodeficiencies using both CD19 and CD20 markers
Assessing therapeutic B-cell depletion quantitatively (absolute counts of cells/mcL) in any clinical context, including malignancies, autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, and membranous glomerulonephritis among others, and treatment or prevention of acute humoral rejection in positive crossmatch renal transplant recipients
This test is not useful for assessing whether B cells express the target molecule (CD20) in the context of initiating therapeutic monoclonal anti-CD20 antibody therapy (rituximab, ofatumumab, and tositumomab) for any of the hematological malignancies, or in other clinical contexts, such as autoimmunity.
Sample Type
Whole Blood
Collection Container
Lavender top tube (EDTA)
Alternative Collection Container
Pink top tube (EDTA)
Collecting Volume
3.0 mL
Minimum Collecting Volume
1.0 mL
Storage or Stability
Ambient - Read instructions below.
Causes for Rejection
Delayed transport. Specimen has been poured off. Gross hemolysis, gross lipemia.
Instructions
Specimen should be collected Monday - Friday only and received in the Raleigh laboratory no later than 1:00 pm,
- It is recommended that specimens be collected in the AM and transported to Raleigh as soon as possible.
- Specimens received after 1:00 pm may not make the shipping deadline and could result in rejection.
- Specimens cannot be collected or shipped on the weekend.
- If collection is to occur within 24 hours of a holiday, please contact the Raleigh Reference Lab section pror to collecting samples.