• Medical School: University of Chicago, Chicago, IL
• Residency: Harvard Medical School, Boston, MA
• Fellowship: Harvard Hand Fellowship, Boston, MA
• Undergraduate: Massachusetts Institute of Technology (MIT), Cambridge, MA

Board Certifications

• American Board of Orthopaedic Surgeons

• 2023 NC Top Doctor Award
• 2022 NC Top Doctor Award
• Jun 2017 Best Clinical Research Award - Harvard Combined Orthopaedics Residency
• Jun 2016 Chief Resident - Massachusetts General Hospital/Harvard Combined Orthopaedics Residency
• Sep 2015 Clinician Scholar Development Program - America Academy of Orthopaedic Surgeons
• May 2015 Resident Teaching Award - Harvard Medical School
• Mar 2014 Best Poster Award - Adult Hip Reconstruction, American Academy of Orthopedic Surgeons Conference
• Oct 2013 Adrian E. Flatt Resident Research Scholarship - American Society of Surgery for the Hand
• May 2012 Leon Jacobson Award for Best Oral Presentation - Senior Scientific Session, University of Chicago Pritzker School of Medicine
• Apr 2012 Best Abstract - International Congress for Joint Reconstruction Conference
• Feb 2012 Best Oral Presentation - Tumor Society, American Academy of Orthopedic Surgeons
• Aug 2011 Fentress Research Fellowship - University of Chicago Pritzker School of Medicine
• Mar 2011 Best Basic Science Presentation - Huggins Research Symposium, University of Chicago Pritzker School of Medicine
• Mar 2011 Best Clinical Presentation - Huggins Research Symposium, University of Chicago Pritzker School of Medicine
• Jun 2010 Pritzker Research Fellowship - University of Chicago Pritzker School of Medicine

Research Publications

Luther G., Blazar P., Dyer G. Achieving Microsurgical Competency in Orthopedic Residents utilizing a Self-Directed Microvascular Training Curriculum. Journal of Bone and Joint Surgery. Feb 2019. PMID: 30730490
Luther G., Murthy, P., Blazar P. Cost of immediate surgery versus non-operative treatment for trigger finger in diabetic patients. Journal of Hand Surgery. Sep 2016. PMID: 27671766
Luther G., Miller P., Mahan S., Waters PM., Bae DS. Decreasing resource utilization using standardized clinical assessment and management plans (SCAMPs). J Pediatric Orthopaedics. Sep 2016. PMID: 27636917
Luther G., Miller P, Waters PM, Bae DS. Radiographic evaluation of pediatric forearm fractures: implications on cost and care. J Pediatric Orthopaedics. Apr 2015. PMID: 25887819
Luther G., Lamplot J., Chen X., Rames R., Wagner E., Shen J., Haydon R., He T.C., Luu H. IGFBP5 Domains Exert Distinct Inhibitory Effects on the Tumorigenicity and Metastasis of Human Osteosarcoma. Cancer Letters. May 2013. PMID 23665505
Luther G., Wagner E., Zhu G., Kang Q., Luo Q., Lamplot J., Bi Y., Luo X., Luo J., Teven C., Shi Q., Kim S., Gao J., Huang E., Rames R., Liu X., Li M., Hu N., Su Y., Chen L., He B.C., Zuo G., Deng Z., Reid R., Luu H., Haydon R., He T.C. BMP-9 Induced Osteogenic Differentiation of Mesenchymal Stem Cells: Molecular Mechanism and Therapeutic Potential. Current Gene Therapy. March 2011. PMID 21453282
Luther G., Rames R., Wagner E., Zhu G., Luo Q., Bi Y., Kim S., Gao J., Huang E., Yang K., Wang L., Liu X., Li M., Hu N., Su Y., Luo X., Chen L., Luo J., Haydon R., Luu H., Zhou L., He T.C. Molecular Basis of Differentiation Therapy for Soft Tissue Sarcomas. Trends in Cancer Research. Jan 2011.
Narayanan AS., Walley KC., Borenstein T., Luther GA., Jackson JB., Gonzalez TA. Surgical Strategies: Necrotizing Fasciitis of the Foot and Ankle Treated with Dermal Regeneration Matrix for Limb Salvage. Foot Ankle Int. Jan 2021
Ordikhani F., Zandi N., Mazaheri M., Luther G., Ghovvatoi M., Akbarzadeh A., Annabi N. Targeted Nanomedicines for the treatment of bone disease and regeneration. Medicinal Research Reviews. Dec 2020
Behzadi S., Luther G., Harris MB., Farokhzad O., Mahmoudi M. Nanomedicine for safe healing of bone trauma: Opportunities and challenges. Biomaterials. Sep 2017.
Lamplot J, Luther G., Mawdsley EL, Luu HH, Manning D. Modified Protocol Decreases Surgical Site Infections after Total Knee Arthroplasty. Journal of Knee Surgery. Mar 2015. PMID 25699629
Lamplot J., Liu B., Zhang W., Wang Z., Luther G., Wagner E., He T.C., Ho S. Reversibly immortalized articular chondrocytes acquire long-term proliferative capability while retaining chondrogenic phenotype. Cell Transplantation. Apr 2014. PMID 24800751
Chen X., Luther G., Zhang W., Nan G., Wagner E., Liao Z., Haydon R., Zhou L., Luu H., He T.C. The E-F hand calcium-binding protein S100A4 regulates the proliferation, survival and differentiation potential of human osteosarcoma cells. Cellular Physiology and Biochemistry. Sep 2013. PMID 24217649
Hekman K., Aliaga L., Straus D., Luther G., Chen J., Sampat., Frim D. Positive and negative predictors for good outcome after decompressive surgery for Chiari malformation type 1 as scored on the Chicago Chiari Outcome Scale. Neurological Research. Sep 2012. PMID 22781921
Aliaga L., Yassari R., Straus D., Hekman K., Luther G., Chen J., Sampat A., Frim D. A Novel Scoring System for Assessing Chiari Malformation Type 1 Treatment Outcomes. Neurosurgery. Mar 2012. PMID 21849925
Teven C., Liu X., Hu N., Tang N., Kim S., Huang E., Yang K., Li M., Gao J., Liu H., Luther G., Luo Q., Wang L., Rames R., Bi Y., Luo J., Luu H., Haydon R., Reid R., He T.C. Epigentic regulation of mesenchymal stem cells: A focus on osteogenic and adipogenic differentiation. Stem Cells and Nuclear Reprogramming. Jul 2011. PMID 21772852
Wagner E., Luther G., Zhu G., Luo Q., Shi Q., Kim S., Gao J., Huang E., Gao Y., Yang K., Wang L., Teven C., Luo X., Liu X., Li M., Hu N., Su Y., Bi Y., He B.C., Haydon R., Luu H., He T.C. Defective Osteogenic differentiation in the development of osteosarcoma. Sarcoma. Feb 2011. PMID 21437219
Pandey S., Luther G., Umanskiy K., Malhotra G., Rubin M., Hurst R., Fichera A. Minimally invasive pouch surgery for ulcerative colitis. Is there a benefit in staging? Diseases of the Colon and Rectum. Feb 2011. PMID 21304301
Rastegar F., Gao J., Shenaq D., Luo Q., Shi Q., Kim S., Jiang W., Wagner E., Huang E., Gao Y., Shen J., Yang K., He B.C., Chen L., Zuo G., Luo J., Luo X., Bi Y., Liu X., Li M., Hu N., Wang L., Luther G., Luu H., Haydon R., He T.C. Lysophosphatidic acid acyltransferase b (LPAATb) promotes tumor growth of human osteosarcoma. PLoS ONE. Dec 2010. PMID 21152068
He B.C., Gao J., Zhang B., Luo Q., Shi Q., Kim S., Huang E., Gao Y., Yang K., Wagner E., Wang L., Tang N., Luo J., Liu X., Li M., Bi., Shen J., Luther G., Hu N., Zhou Q., Luu H., Haydon R., Zhao Y., He T.C. Tetrandrine Inhibits Wnt/ β-Catenin Signaling and Suppresses Tumor Growth of Human Colorectal Cancer. Molecular Pharmacology. Oct 2010. PMID 20978119
Teply B., Tong R., Jeong S., Luther G., Sherifi I., Yim C., Khademhosseini A., Farokhzad O., Langer R., Cheng J. The use of charge-coupled polymeric microparticles and micromagnets for modulating the bioavailability of orally delivered macromolecules. Biomaterials. Dec 2007. PMID 18082254
Cheng J., Teply B., Sherifi I., Sung J., Luther G., Gu F., Nissenbaum E., Moreno A., Langer R., Farokhzad O. Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery. Biomaterials. Feb 2007. PMID 17055572

Podium Presentations

Luther G., Blazar P, Dyer, G. Effectiveness of a microvascular training curriculum utilizing nonliving models. Richard J. Smith Annual Research Symposium. April 2017.
Luther G., Miller P, Mahan, S, Waters PM, Bae DS. Decreasing resource utilization using standardized clinical assessment and management plans (SCAMPs). Richard J. Smith Annual Research Symposium. May 2014.
Lamplot J., Luther G., Luu H., Manning D. Aseptic protocol decreases surgical site infections following hip arthroplasty. Mid-America Orthopaedic Association Annual Meeting. Apr 2014.
Lamplot J., Luther G., Krummenacher T., Hussain M., Luu H., Manning D. Aseptic protocol decreases surgical site infection after knee arthroplasty. American Academy of Orthopaedic Surgeons (AAOS) Annual Conference. Mar 2014.
Luther G., Miller P, Waters PM, Bae DS. Radiographic evaluation of pediatric forearm fractures: implications on cost and care. American Academy of Orthopaedic Surgeons (AAOS) Annual Conference. Mar 2014.
Luther G., Miller P, Waters PM, Bae DS. Radiographic evaluation of pediatric forearm fractures: implications on cost and care. Richard J. Smith Annual Research Symposium. May 2013.
Luther G., Stack M, Manning D. A novel aseptic protocol decreases surgical site infections following total hip and revision hip arthroplasty. International Congress for Joint Reconstruction (Apr 2012), MidAmerica Orthopaedics Association Annual Meeting (Apr 2012)
Luther G., Wagner E, Rames R., Lamplot J., Haydon R, He T.C., Luu H. Functional characterization of IGFBP-5 in the inhibition of osteosarcoma tumorigenicity. American Academy of Orthopaedic Surgeons (AAOS) Annual Conference- Tumor Society Best Oral Presentation. Feb 2012.
Luther G., Rames R., Wagner E., Lamplot J., Haydon R., He T.C., Luu H. Mechanism of Osteosarcoma tumorigenesis by S100A4. American Academy of Orthopaedic Surgeons (AAOS) Annual Conference. Feb 2012.
Luther G., Rames R, Wagner E, Haydon R, He T.C., Luu H. Functional characterization of IGFBP-5 in the inhibition of osteosarcoma tumorigenicity. Huggins Research Symposium: Winner of Best Basic Science Presentation. Apr 2011.
Rames R, Luther G., Lamplot J, Wagner E, Luu H, He T.C. Induction of chondrogenic differentiation in Mesenchymal Stem Cells using a novel combination of Sox Transcription Factors and Bone Morphogenetic Proteins. Huggins Research Symposium: Winner of Best Clinical Presentation. Apr 2011.
Wagner E., Luther G., Haydon R., He T.C., Luu H. The mechanism underlying the inhibition of osteosarcoma tumorgenecity by IGFBP5. American Academy of Orthopaedic Surgeons (AAOS) Annual Conference. Feb 2011.

Poster Presentations

Luther G., Jeffs A. Radial Sensory Nerve to AIN Transfer for Symptomatic RSN Neuromas. American Society for Surgery of the Hand (ASSH) Annual Conference. Aug 2022.
Luther G., Blazar P., Dyer G. Development of a low-cost, high-fidelity resident microsurgical training curriculum. American Society for Surgery of the Hand (ASSH) Annual Conference. Oct 2017.
Luther G., Murthy, P., Blazar P. Cost of immediate surgery versus non-operative treatment for trigger finger in diabetic patients. American Society for Surgery of the Hand (ASSH) Annual Conference. Oct 2016
Luther G., Miller P, Mahan, S, Waters PM, Bae DS. Decreasing resource utilization using standardized clinical assessment and management plans (SCAMPs). American Academy of Orthopaedic Surgeons (AAOS) Annual Conference. Mar 2015.
Lamplot J., Luther G., Borque K., Luu H.H., Manning D.W. Aseptic protocol decreases surgical site infection after hip arthroplasty. American Academy of Orthopaedic Surgeons (AAOS) Annual Conference. Mar 2014.
Luther G., Miller P, Waters PM, Bae DS. Radiographic evaluation of pediatric forearm fractures: implications on cost and care. American Society for Surgery of the Hand (ASSH) Annual Conference. Oct 2013.
Lamplot J., Luther G., He T.C., Luu H. Methylation of IGFBP5 promoter regulates human osteosarcoma. Orthopaedic Research Society (ORS) Annual Conference. Jan 2013.
Luther G., Stack M, Rames R, Manning D. A novel aseptic protocol decreases surgical site infections following total hip and revision hip arthroplasty. International Congress of Joint Reconstruction. Apr 2012.
Luther G., Rames R., Wagner E., Haydon R., He T.C., Luu H. Inhibition of Osteosarcoma metastasis by Insulin Growth Factor Binding Protein 5 (IGFBP5). Orthopaedic Research Society (ORS) Annual Conference. Feb 2012.
Luther G., Rames R., Wagner E., Haydon R., He T.C., Luu H. Mechanism of Osteosarcoma tumorigenesis by S100A4. Orthopaedic Research Society (ORS) Annual Conference. Feb 2012.
Luther G., Rames R, Wagner E, Haydon R, He T.C., Luu H. Functional characterization of IGFBP-5 in the inhibition of osteosarcoma tumorigenicity. American Society of Clinical Oncology (ASCO) Annual Conference. Jun 2011.
Luther G., Stack M, Manning D. Use of trabecular metal components in revision hip arthroplasty. Huggins Annual Research Symposium. Apr 2011.
Luther G., Stack M, Rames R, Manning D. Surgical site infections following total hip and revision hip arthroplasty. Huggins Annual Research Symposium. Apr 2011.
Luther G.Luther G, Wagner E, Rames R, Haydon R, He T.C., Luu H. S100A6 is a novel inducer of osteosarcoma tumorigenicity. Huggins Annual Research Symposium. Apr 2011.
Luther G.Luther G, Rames R, Wagner E, Haydon R, He T.C., Luu H. Functional characterization of IGFBP-5 in the inhibition of osteosarcoma tumorigenicity. Huggins Annual Research Symposium. Apr 2011.
Rames R, Luther G., Lamplot J, Wagner E, Luu H, He T.C. Establishment and characterization of a novel murine chondrocytic cell line. Huggins Annual Research Symposium. Apr 2011.
Rames R, Luther G., Lamplot J, Wagner E, Luu H, He T.C. Induction of chondrogenic differentiation in Mesenchymal Stem Cells using a novel combination of Sox Transcription Factors and Bone Morphogenetic Proteins. Huggins Annual Research Symposium. Apr 2011.
Luther G.Luther G., Wagner E., Haydon R., He T.C., Luu H. Delineating the Role of S100A6 in Osteosarcoma and Osteogenic Differentiation. Orthopaedic Research Society (ORS) Annual Conference. Jan 2011.
Luther G.Luther G., Wagner E., Haydon R., He T.C., Luu H. The Mechanism Underlying the Inhibition of Osteosarcoma Tumorigenicity by IGFBP5. Orthopaedic Research Society (ORS) Annual Conference. Jan 2011.

The Star Ratings score is the average score a provider receives about his or her care on our Patient Satisfaction Survey conducted by Professional Research Corporation. Responses are on a scale of 1 to 5 with 5 being the best score. The Star Rating you see represents the average score a provider received for the past 12-month period as long as they had more than 30 ratings during that time frame.

4/20/2023 The eye contact when listening to his patient. Bedside manner was very respectful

4/17/2023 Really liked Luther

4/15/2023 My final visit . Dr. Luther and staff have been very friendly and supportive following my hip surgery. Excellent care!

4/13/2023 Compassionate care.

4/13/2023 I really like the fact that Dr. Luther includes the patient in all decisions made

4/7/2023 Doctor Luther and all his staff were very professional, efficient, and friendly.

4/3/2023 Dr Luther is amazing caring and explains things very well! Spoke to my son in a way he could understand and be apart of the decision and conversation!

4/2/2023 The staff was efficient - doctor on time, and personable ........ good listener, and caring .......... overall excellent experience ......

3/31/2023 Professionalism and knowledge of my Doctor

3/23/2023 the doctor was very good

3/20/2023 from entering the office to my exit, i had absolutely no problems,

3/19/2023 Fortunate I had no wait at all. Being on time is important. It was a followup visit and I was in and out in no time.

3/18/2023 Dr. Luther is excellent. Caring, knowledgeable, great interaction.

3/16/2023 Dr. Luther care and concern are outstanding. We appreciate Debbie and Melissa. They go above and beyond with their care and concern.

3/14/2023 Dr Luther is a great dr. He really has great way of explaining what's going on to make you feel comfortable with the tx process. Very personable. His staff is pleasant and easy going. Thxs Apex team

3/13/2023 The physician was excellent

3/11/2023 Dr Luther! Incredible physician, listener…speaks in human terms . One feels extremely confident in a plan of care and his knowledge. Feel fortunate to have him helping me.

3/9/2023 Dr. Luther has been SO great! He gave us our options and has explained everything thoroughly with my husband and I!

3/7/2023 Dr Luther was very professional and caring while executing outstanding service and treatment. More providers/physicians should follow in his steps.

3/2/2023 The tech was extremely nice and helpful. Dr. Luther was great

3/2/2023 The attention to detail that Dr Luther does is outstanding

2/25/2023 The whole visit was outstanding front start to finish

2/23/2023 Dr Luther and his team are so great to work with. Genuinely care about how their patients are doing and never seemed rushed.

2/23/2023 Dr Luther and the whole team were great. I could not stand my cast and I was afraid they would treat me as if I were mentally ill. Everyone was extremely understanding and friendly. The PA on-site came up with an alternative plan and when I followed up I was out in a different brace. I was impressed and grateful for their professionalism and grace.

2/22/2023 I cannot complain about anyone or anything at Dr. Luther's office. They are all exceptional. Dr. Luther and Christy expressed care and compassion.

2/21/2023 Dr Luther is a very caring doctor. He takes time with me and explains what treatment I need. I will definitely recommend him to my friends and family.

2/20/2023 Very pleased with the care I received

2/15/2023 Great visit, no complaints

2/12/2023 Dr. Luther and his entire staff at the facility was wonderful

2/11/2023 Dr. Luther was professional, kind, and thorough. He explained the healing process. I felt reassured that he wanted to see me in 10 days to make sure that my elbow was healing properly.

2/8/2023 He has been outstanding through this entire process.

2/7/2023 An overall good experience with Wake Med and Dr Luther.

2/7/2023 Genuinely concerned and anxious to resolve pain in the most effective way. Received surgery today and staff was exceptional. Each person had the best bedside manner.

2/6/2023 Willingness to ensure I received the treatment that was needed. Flexibility wascgreat too.

2/2/2023 Dr. Luther, nurses, and all the staff were very caring and took excellent care of me during my stay.

2/2/2023 Great Customer Service and treatment!!!!

1/23/2023 Everyone was helpful and responsive

1/21/2023 Everything went smoothly. I did not have to wait a long time in the waiting room. Overall, I was very pleased.

1/21/2023 Every one there is helpful, attentive & professional. Grateful for the excellent care I can depend on!

1/21/2023 Everyone working that day was amazing. I felt so comfortable the entire time.

1/19/2023 Dr. Luther and his nurse, Debbie, were excellent.