Tricyclic Crossreactivity Table
Compound | Conc.(ng/mL) | Effect |
Amitriptyline | 250 | Positive |
Amoxapine | 100,000 | Positive |
Chlorpromazine | 1300 | Positive |
Clomipramine | 350 | Positive |
Cyclobenzaprine | 400 | Positive |
Desimipramine | 250 | Positive |
Doxepin | 550 | Positive |
Imipramine | 200 | Positive |
Nortriptyline (reference drug) | 300 | Positive |
Trimipramine | 300 | Positive |
2-Hydroxy-Imipramine | 1700 | Positive |
Acetaminophen | 1000 | Negative |
Carbamazepine | 100 | Negative |
Dextromethorphan | 1000 | Negative |
Ethchlorvynol | 500 | Negative |
Methaqualone | 100 | Negative |
Meperidine | 100 | Negative |
Perphenazine | 0.4 | Negative |
Phenobarbital | 500 | Negative |
Primidone | 100 | Negative |
Propoxyphene | 500 | Negative |
Secobarbital | 500 | Negative |
Amphetamine | 500 | Negative |
Cocaine | 100 | Negative |
Diazepam | 100 | Negative |
Maprotiline | 2 | Negative |
Methsuximide | 100 | Negative |
Morphine | 100 | Negative |
Phencyclidine | 1000 | Negative |
Phenytoin | 100 | Negative |
Promethazine | 500 | Negative |
Trazodone | 5 | Negative |
Valproic acid | 500 | Negative |
top of page | 3/1/05 |
Tricyclic compounds and other structurally related compounds were tested for cross reactivity in the assay. The table lists the concentrations of the compounds that produce a positive result in the assay using 300 ng/mL nortriptyline as cut-off calibrator.